Metabolomics Industry Resources

Metabolomics presents challenges from sample introduction to the analytical methods used, and the data reduction required to interpret the results. No single analytical technique can be used for complete characterization of the metabolome, and no metabolome has ever been completely characterized.

Despite these challenges, LECO’s just-in-time derivatizer coupled with the Gas Chromatography Mass Spectrometers (GC-MS) provides an established method to introduce samples into the GC-MS and analyze the primary metabolome, whereas other techniques simply investigate the secondary and tertiary metabolites. One of the principal challenges in metabolomics is the detection and identification of unknowns; you need to know what else is in your sample to successfully characterize it, and our GC-MS solutions give you a clear advantage. Our solutions have a robust automated derivatization and sample introductory method, separation, accuracy, resolving power, deconvolution, and speed to characterize the most complex metabolite profiles.

Instrument Portfolio

Pegasus Two-Dimensional Gas Chromatograph
Pegasus BT 4D

GCxGC Time-of-Flight Mass Spectrometer

Pegasus High-Resolution Gas Chromatograph
Pegasus GC-HRT

High Resolution GC-TOFMS

Pegasus High Resolution two-dimensional gas chromatograph
Pegasus GC-HRT 4D

High Resolution GCxGC-TOFMS

News or Stories

1 November 2021 Metabolomics and GCxGC are Changing How We Monitor Our Health

Learn how Jane Hill is using GCxGC and the study of metabolomics to develop a new method of diagnosing lung infections.

19 March 2020 Medical Investigation using Breath Analysis and GCxGC-TOFMS: Optimizing Data for Accurate Treatment

Using GC-GC-TOFMS, Jef Focant is able to diagnose the asthma phenotype in patients.