GC-MS
Gas Chromatography/Mass Spectrometry (GC-MS, GCMS or GC/MS) is an analytical method that is used to determine the composition of substances within a test sample. As the name describes, the system is composed of a gas chromatograph to separate the substances (analytes) and a mass spectrometer to identify these analytes. This is the gold standard for analysis in many fields such as forensics or petrochemical studies as GC-MS allows for the unequivocal identification of substances.
Instrument Portfolio
Application Notes
Learn more about our solutions for GC-MS with our library of related application notes.
| 203-821-662 | A Comprehensive GC-TOFMS Metabolomics Workflow Early Type 2 Diabetes prediction can be facilitated by the implementation of a metabolomics method for the identification of T2DM biomarkers. A complete automated derivatization workflow is explored. |
News or Stories
Since the first humans walked the earth, our species has been changing the world. Brilliant minds throughout existence have provided us with life-altering inventions and ideas, like medicines that cure our ailments and lengthen our lives, or technology that connects us in ways we never thought possible. The human mind has thought up some incredible […]
St. Patrick’s Day is an annual feast day celebrating the patron saint, St. Patrick. It’s a national holiday in both Ireland and Northern Ireland. The holiday, taking place on March 17th, has a number of traditions associated with it here in the USA as well—wearing green, eating the traditional Irish corned beef and cabbage, the […]
LECO, in partnership with The Analytical Scientist, is pleased to announce the winners of our Application Challenge! Learn more about novel and interesting applications of GC-MS through interviews with the winners.
Videos and Webinars
- 1State of the Art Technology – Aroma, Flavour, and Fragrance From 26 September 1987
- 2Time-of-Flight and Quadrupole Mass Analyzers for Gas Chromatography From 12 November 2009
- 3Evolution of Time-of-Flight Mass Spectrometry within the Pharmaceutical Industry From 29 March 2012
- 4High Resolution GCMS Applications in Metabolomics From 21 February 2013
- 5Advanced Instrument Development and Applications for Harsh Environments From 18 July 2013
- 6Dramatically Increase Information Content in Metabolomics Studies From 24 October 2013
Posters and Presentations
- Automated Sample Derivatization for High-Throughput Drug Testing by SAMHSA Guidelines Urine samples were analyzed according to Substance Abuse and Mental Health Service Administration guidelines for workplace drug testing.
- Breath Analysis for Disease Interrogation Breath volatomes were analyzed via GCxGC-TOFMS to demonstrate possible future of metabolomic studies.
- Forensics Analysis Workflow using EI & CI in HRTOFMS Controlled substances, such as marijuana, cocaine, heroin and methamphetamines, are commonly seized by law enforcement officials and routinely analyzed by forensic laboratories. Explore how HRTOFMS using Electron and Chemical Ionization can analyze these substances.
- Determining High-Concentration Aromatic Compounds in Gasolines (ASTM D5769) Using CG-TOFMS ASTM D5769 is a widely accepted standard method used in the petroleum industry for determination of benzene, toluene, and total aromatics in finished gasolines by GC-MS. A common difficulty encountered with this method is the concern with saturation of the ion source, which leads to nonlinearity in calibration curves, especially for the quantification of the high-concentration aromatics, such as toluene.
- Accurate Deconvolution by Exploiting Differential Expressions A set of chromatography-mass spectrometry data for multiple related samples may be considered as a tensor with spectral, retention, and experimental dimensions.