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When you don't know what you're looking for, as is often the case with environmental contaminants and pollutants, the task can seem daunting, but high-resolution TOFMS and GCxGC is a powerful combination for non-target searches. With the tools included with the Pegasus® HRT4D and the Multi-Mode Source™ (MMS™), identification of unknowns can be vastly improved and assigned higher confidence.

Small time savings throughout the workflow can add up to big savings. See aroma and flavor examples of how automated sample prep and elevated Time-of-Flight Mass Spectrometry (TOFMS) analysis, followed by software solutions to compare and evaluate data and results, can save your lab time and resources.

Helium is becoming an increasingly limited natural resource; using Hydrogen to achieve increased chromatographic throughput in GC applications is attractive. Both have advantages and disadvantages. LECO experts investigated the use of Hydrogen as a carrier gas for GC-TOF-MS analysis. Nick Jones, LECOs Global Application and Development Director (Separation Sciences) presents the method transfer approaches used, the technological benefits, and application examples in the presentation below.

How do we find what we don't specifically look for? This presentation will look at non-target GCxGC for environmental forensics, or exposomic analysis, of wastewater, specifically the semivolatile organic fraction, and what can be done when discovered non-targets may present health impacts. Frank L. Dorman, Penn State University Dept of Biochemistry and Molecular Biology & Dartmouth College Dept of Chemistry

Three GC/MS Experts embrace the 'spookier' side of mass spectrometry.

Jane Hill, from the University of British Columbia, brings her expertise on 'omics and medical diagnostics in Disease: Trick or Treat? Metabolomics is changing how we monitor our health

Albert Lebedev, professor at the Faculty of Chemistry at Moscow State University, has suggestions and advice for what to do if you meet a mummy (and happen to have access to mass spectrometry!) in What Mass Spectrometry can tell you about 5000 year old Mummies

Shari Forbes, Director of Canada's Secure Site for Research in Thanatology, will finish the symposium with a look into GCxGC mass spectrometry and the wider range of research and training that can come from Canada's first body farm in Death, Decomposition and Dogs

The Czech Agriculture and Food Inspection Authority has been using GCxGC-TOFMS for the analysis of pesticide residues in food of plant origin since 2005. Radim Stepan will talk about the advances in the instruments and the analyses they have used for pesticide residue analysis in cooperation with the University of Chemistry and Technology Prague.

The current analytical method for the quantitative determination of Mineral Oil Saturated Hydrocarbons (MOSH) and Mineral Oil Aromatic Hydrocarbons (MOAH) is LC-GC-FID, but the chromaticagraphic profile obtained is too often just a hump of unresolved substances. However, GCxGC-TOFMS/FID is the most promising solution to characterize MOSH and MOAH in detail and to detect markers that can help identify and act on the source of contamination. Giorgia Purcaro [University of Liege] will introduce the challenges of MOSH/MOAH analysis and talk about what adding a GCxGC-TOFMS analysis to your process can do for your results.

Lorne Fell [LECO] provides an update on LECO Separation Science instruments and equipment. Jean-François Focant [University of Liège] presents "Multiclass GCxGC Method for Cannabis Products", discussing how GCxGC can be utilized to study cannabis strains for CBD content.

Rob Synovec [University of Washington] discusses discovery-based analysis and its application into gas chromatography, and the development of ChromaTOF® Tile, a tile-based fisher ratio analysis tool. [Synovec presentation begins at 14:00]

Liz Humston-Fulmer [LECO] utilized GCxGC TOF-MS technologies to understand the chemical composition of CBD-infused beverages. Originally presented 26 March 2020.

Dave Alonso explores GCxGC TOFMS analysis of cannabis samples for understanding of terpene and cannabinoids among cannabis cultivars.

Dave Alonso explores GCxGC TOFMS analysis of cannabis samples for understanding of terpene and cannabinoids among cannabis cultivars.

Liz Humston-Fulmer [LECO] utilized GCxGC TOF-MS technologies to understand the chemical composition of CBD-infused beverages.

Lorne Fell [LECO] briefly discusses comprehensive two-dimensional gas chromatography, and demonstrates how to establish GCxGC methods utilizing the Simply GCxGC software.

John Seeley [Oakland University] discusses various modulation technique for sample introduction into GCxGC columns.

Thomas Groger [University of Rostock] discusses the benefits that GCxGC provided their laboratory with the study of crude oils, bitumen, and various high boilers (solvents added to slow evaporation rates).

"Better, Greener, Faster" Webinar presented by Bob Nelson and Chris Reddy, from the Woods Hole Oceanic Institution, September 2017.

Mark Merrick [LECO] overviews comprehensive two-dimensional gas chromatography, and introduces Simply GCxGC, a comprehensive 2D gas chromatography method optimization online tool.