Derivatization is essential for ensuring that highly polar analytes, like sugars and free fatty acids, can be effectively separated for gas chromatographic analysis. This step is especially important in metabolomics, where the wide range of chemical properties can complicate workflows and reduce data consistency. Traditional batch derivatization, however, can lead to degradation over time, impacting reliability and repeatbility.
Automating this process solves that challenged. The L-PAL3 Derivatizer, which debuted at Pittcon 2023, brings fully-automated just-in-time derivatization into your laboratory, enabling precise, reliable two-stage derivatization across an entire sample tray.
Unlike other just-in-time derivatizers on the market, LECO’s is already tied into the powerful ChromaTOF brand software for seamless workflow integration. No additional programs are needed, as the intuitive method design process of ChromaTOF has been expanded to include sample prep overlapping and scheduling. With this new tool in its belt, LECO’s GC-TOFMS delivers the sensitivity and full mass-range acquisition required for both targeted and non-targeted metabolomics workflows.
Add just-in-time derivatization to your Pegasus for true set-it-and-forget-it automation in your workflow.
